Drug Development for Malaria: Novel Approaches for Prevention and Treatment

Provides readers with first-hand advice for the development of novel antimalarial drugs

This book provides a systematic overview of antimalarial drug development and presents a wealth of data and insight from drug developers across three continents, including many from countries where the disease is endemic. Throughout, the contributions have been written with the drug developer in mind, highlighting challenges but also opportunities for the successful development of effective antimalarial drugs. Case studies and method-oriented chapters provide an abundance of practical first-hand advice on how to successfully develop an antimalarial drug.

Key topics covered in the book include:

• The performance of current drugs and therapies, the influence of formulation and targeted delivery, and strategies to overcome drug resistance.
• Technologies and approaches for development of novel drugs, such as assays, computer-aided drug design, known and potential drug targets, and natural sources for novel antimalarial compounds
• Vaccination as an alternative to drug therapy

For chemists and other professionals working in industries related to medicine and pharmaceuticals, this book provides a completely comprehensive overview of the current state of novel antimalarial drugs and how they can be developed in an efficient and cost-effective manner.